8-K - Karyopharm Therapeutics Inc. (0001503802) (Filer)
Published . Updated .
Key takeaways
- 8-K - Karyopharm Therapeutics filed an 8-K with the SEC on Nov 3 (a notice of a material company event).
- Exposed: KPTI
- Market reaction: KPTI −53.8% after three sessions
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8-K - Karyopharm Therapeutics filed an 8-K with the SEC on Nov 3 (a notice of a material company event).
Directly affected
- KPTI Karyopharm Therapeutics-90.5% 30d
Named in this report.
Indirectly affected
- XLV Health Care Select Sector SPDR
Health Care Select Sector SPDR holds the health sector that Karyopharm Therapeutics belongs to, so it often moves with news about it.
- LLY Eli Lilly and+15.5% 30d
Eli Lilly and is a peer of Karyopharm Therapeutics in pharmaceutical preparations; rivals often move on the same news.
- JNJ Johnson & Johnson+0.1% 30d
Johnson & Johnson is a peer of Karyopharm Therapeutics in pharmaceutical preparations; rivals often move on the same news.
- ABBV AbbVie+9.0% 30d
AbbVie is a peer of Karyopharm Therapeutics in pharmaceutical preparations; rivals often move on the same news.
- MRK Merck+3.5% 30d
Merck is a peer of Karyopharm Therapeutics in pharmaceutical preparations; rivals often move on the same news.
- ABT Abbott Laboratories+10.3% 30d
Abbott Laboratories is a peer of Karyopharm Therapeutics in pharmaceutical preparations; rivals often move on the same news.
Price reaction, T-5 to T+3
| Ticker | T-5 | T-3 | T-1 | T0 | T+1 | T+2 | T+3 |
|---|---|---|---|---|---|---|---|
| KPTI | +323.43% | +679.25% | base | -18.78% | -25.76% | -44.90% | -53.76% |
| XLV | -2.95% | -0.31% | base | -0.34% | +2.73% | +0.31% | +0.13% |
| LLY | -9.22% | -2.71% | base | -0.17% | +0.45% | -2.64% | -4.04% |
| JNJ | -0.68% | +1.70% | base | -1.63% | +2.13% | +0.67% | +2.13% |
| ABBV | -0.84% | +0.67% | base | -1.01% | +1.62% | +0.12% | +0.94% |
| MRK | -4.45% | -1.43% | base | -2.55% | +1.29% | -0.75% | -1.14% |
| ABT | -6.49% | -5.19% | base | -0.80% | +5.08% | +2.96% | -0.28% |
Closing-price change versus T-1, the last close before the story. T0 to T+3 fill in after each market close. Prices: Alpaca IEX.
Filed: 2026-11-03 AccNo: 0001193125-26-444164 Size: 2 MB Item 1.01: Entry into a Material Definitive Agreement Item 1.03: Bankruptcy or Receivership Item 2.03: Creation of a Direct Financial Obligation or an Obligation under an Off-Balance…
Source: sec-edgar
Karyopharm Therapeutics (KPTI)
Across 3 earlier stories, Karyopharm Therapeutics (KPTI) the next day averaged -38.57%. The largest gain was -11.83% and the largest drop was -85.85%, from 3 prices.
| Company | When | Average | Largest gain | Largest drop | Prices |
|---|---|---|---|---|---|
| Karyopharm Therapeutics (KPTI) | the next day | -38.57% | -11.83% | -85.85% | 3 |
| Karyopharm Therapeutics (KPTI) | three days later | -18.98% | +52.35% | -90.40% | 3 |
Karyopharm Therapeutics (KPTI) since this story, compared with the market
Since the first closing price after “8-K - Karyopharm Therapeutics Inc. (0001503802) (Filer),” Karyopharm Therapeutics (KPTI) is -25.78%.
| Company | When | Move | Status |
|---|---|---|---|
| ABBV | that day | -1.01% | final price |
| ABBV | the next day | +1.62% | final price |
| ABBV | two days later | +0.12% | final price |
| ABBV | three days later | +0.94% | final price |
| ABBV | three days earlier | +0.67% | final price |
| ABBV | five days earlier | -0.84% | final price |
| ABT | that day | -0.80% | final price |
| ABT | the next day | +5.08% | final price |
| ABT | two days later | +2.96% | final price |
| ABT | three days later | -0.28% | final price |
| ABT | three days earlier | -5.19% | final price |
| ABT | five days earlier | -6.49% | final price |
| JNJ | that day | -1.63% | final price |
| JNJ | the next day | +2.13% | final price |
| JNJ | two days later | +0.67% | final price |
| JNJ | three days later | +2.13% | final price |
| JNJ | three days earlier | +1.70% | final price |
| JNJ | five days earlier | -0.68% | final price |
| Karyopharm Therapeutics (KPTI) | that day | -18.78% | final price |
| Karyopharm Therapeutics (KPTI) | the next day | -25.76% | final price |
| Karyopharm Therapeutics (KPTI) | two days later | -44.90% | final price |
| Karyopharm Therapeutics (KPTI) | three days later | -53.76% | final price |
| Karyopharm Therapeutics (KPTI) | three days earlier | +679.25% | final price |
| Karyopharm Therapeutics (KPTI) | five days earlier | +323.43% | final price |
| LLY | that day | -0.17% | final price |
| LLY | the next day | +0.45% | final price |
| LLY | two days later | -2.64% | final price |
| LLY | three days later | -4.04% | final price |
| LLY | three days earlier | -2.71% | final price |
| LLY | five days earlier | -9.22% | final price |
| MRK | that day | -2.55% | final price |
| MRK | the next day | +1.29% | final price |
| MRK | two days later | -0.75% | final price |
| MRK | three days later | -1.14% | final price |
| MRK | three days earlier | -1.43% | final price |
| MRK | five days earlier | -4.45% | final price |
| XLV | that day | -0.34% | final price |
| XLV | the next day | +2.73% | final price |
| XLV | two days later | +0.31% | final price |
| XLV | three days later | +0.13% | final price |
| XLV | three days earlier | -0.31% | final price |
| XLV | five days earlier | -2.95% | final price |
Congressional trades in the stocks in this story
- Rep. Rohit Khanna bought Eli Lilly (LLY) (held by a spouse), worth $1,001 - $15,000 on 4 Sep 2026. That is 60 days before publication. Filed 7 Oct 2026. View the filing.
- Rep. Thomas H. Kean Jr sold Johnson & Johnson (JNJ), worth $1,001 - $15,000 on 30 Sep 2026. That is 34 days before publication. Filed 30 Oct 2026. View the filing.
- Rep. Rohit Khanna bought Johnson & Johnson (JNJ) (held by a spouse), worth $1,001 - $15,000 on 25 Sep 2026. That is 39 days before publication. Filed 7 Oct 2026. View the filing.
- Rep. Lloyd Doggett bought Johnson & Johnson (JNJ), worth $1,001 - $15,000 on 8 Sep 2026. That is 56 days before publication. Filed 5 Oct 2026. View the filing.
- Rep. Pete Sessions sold AbbVie (ABBV), worth $15,001 - $50,000 on 14 Sep 2026. That is 50 days before publication. Filed 18 Sep 2026. View the filing.
- Rep. Rohit Khanna sold AbbVie (ABBV) (held by a spouse), worth $1,001 - $15,000 on 4 Sep 2026. That is 60 days before publication. Filed 7 Oct 2026. View the filing.
- Rep. Maria Elvira Salazar sold Merck (MRK), worth $1,001 - $15,000 on 24 Sep 2026. That is 40 days before publication. Filed 7 Oct 2026. View the filing.
- Rep. Maria Elvira Salazar bought Merck (MRK), worth $15,001 - $50,000 on 19 Aug 2026. That is 76 days before publication. Filed 9 Sep 2026. View the filing.
- Rep. Pete Sessions sold Abbott Laboratories (ABT) (held by a spouse), worth $50,001 - $100,000 on 2 Oct 2026. That is 32 days before publication. Filed 27 Oct 2026. View the filing.
- Rep. Gilbert Cisneros bought Abbott Laboratories (ABT), worth $1,001 - $15,000 on 18 Sep 2026. That is 46 days before publication. Filed 12 Oct 2026. View the filing.
- Rep. Thomas H. Kean Jr sold Abbott Laboratories (ABT), worth $1,001 - $15,000 on 17 Sep 2026. That is 47 days before publication. Filed 30 Oct 2026. View the filing.
Public disclosure filings, not a recommendation. The filing link is the source document. News use of these reports still sits under 5 U.S.C. § 13107(c).
Who gains and who loses around Karyopharm Therapeutics (KPTI)
Companies tied to this story
- KPTI Karyopharm Therapeutics
Karyopharm Therapeutics (KPTI) is linked, with no stored direction, high confidence in the 3 Nov 2026 story “8-K - Karyopharm Therapeutics Inc. (0001503802) (Filer).” Reason on file: SEC 8-K filing -> direct issuer disclosure -> KPTI
How “8-K - Karyopharm Therapeutics Inc. (0001503802) (Filer)” reaches Karyopharm Therapeutics (KPTI)
On 3 Nov 2026, “8-K - Karyopharm Therapeutics Inc. (0001503802) (Filer)” is the story that connects Karyopharm Therapeutics (KPTI) to this story.
The link for Karyopharm Therapeutics (KPTI) is this: SEC 8-K filing -> direct issuer disclosure -> KPTI
Price levels for Karyopharm Therapeutics (KPTI)
KPTI traded between 0.05 and 0.94 across 20 sessions. The latest close on file is 0.06.
What the saved facts support for Karyopharm Therapeutics (KPTI)
14 out of 100
“8-K - Karyopharm Therapeutics Inc. (0001503802) (Filer)” scores 14 out of 100. The score uses 1 sources, and 1 linked companies.